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Led by authors from MD Anderson’s Stem Cell Transplantation and Cellular Therapy Department, the world’s largest and highly respected program at the forefront of rapidly advancing treatments in the field, Manual of Hematopoietic Cell Transplantation and Cellular Therapies is a comprehensive, focused reference covering the latest clinical developments and applications of stem cell transplant and cellular therapies for hematologic malignancies and solid tumors. This cutting-edge title, with a majority contribution from the MD Anderson Cancer Center and leading faculty from other academic institutions, covers breakthrough cell-based therapies for various diseases including lymphoma, multiple myeloma, leukemia, and select solid tumor and autoimmune diseases. This unique, definitive resource is essential for hematologists, fellows in hematology and immunotherapy, mid-level providers, pharmacists, and oncologists who refer patients for cell-based therapies. Key Features
Addresses hematologic conditions including leukemia, lymphoma, and myeloma.
Offers guidance on hematopoietic cell transplantation for solid tumors.
Covers basic science principles, clinical aspects, pharmacology, radiation therapy, and disease-specific guidelines, including prevention and management of complications.
Discusses key topics such as hematopoietic cell collection, bone marrow harvesting, umbilical cord blood transplantation, CAR T-cell therapy, and patient/donor selection and preparation of HCT.
Features extensive summary boxes, bulleted content, and algorithms throughout for quick and easy reference.
Offers team-based, clinically-focused coverage from world-renowned leaders in the field.
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Author Information
Edited by Qaiser Bashir, MD, Associate Professor of Medicine, Department of Stem Cell Transplantation & Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas; Elizabeth J. Shpall, MD, Professor and Chair, at interim, Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine Director, Cell Therapy Laboratory, Director, Cord Blood Bank, The University of Texas MD Anderson Cancer Center, Houston, Texas and Richard E. Champlin, MD, Professor, Department of Stem Cell Transplantation and Cellular Therapy, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas-도서목차-
1 Evolution of HCT, past, present, and future
2 Biology of HSC and other cells
2 HLA typing
3 Hematopoietic cell collection
4 Functions of Cell Therapy lab
4 Bayesian statistical methods in HCT and cellular therapies
4 Introduction and basic science of chimeric antigen receptor therapies
5 Patient and donor assessment and preparing for HCT
6 General management of patients undergoing HCT
7 Haploidentical HCT
8 Umbilical cord blood transplantation
9 Process and general management of patients undergoing CAR therapies
10 Preparative regimens used in HCT and CAR therapies
11 Pharmacology of drugs used in HCT and CAR therapies
12 Radiobiologic principles and the role of radiotherapy in hematopoietic stem cell transplant and CAR T-cell therapy
13 Hematopoietic Cell Transplantation in Adult with Acute Myeloid Leukemia
14 CAR therapy in AML
15 HCT in ALL
16 CAR therapy in ALL
17 HSCT in CLL
18 HCT in MDS
19 Allogeneic stem cell transplantation for myeloproliferative neoplasms
20 HCT in aplastic anemia
21 HCT in multiple myeloma
22 CAR therapy in multiple myeloma
23 HCT in light-chain amyloidosis
24 HCT in NHL
25 HCT in Hodgkin lymphoma
26 CAR therapy in lymphoma
27 HCT in rare malignancies
28 HCT in solid tumors
30 Monitoring for relapse and DLI
30 Infection control, prophylaxis, and vaccinations
31 Management of infections in HCT
32 Graft Failure After Hematopoietic Cell Transplantation
33 Graft-versus-host disease
34 HCT in AML
34 CAR therapy in AML
34 HCT in ALL
34 Miscellaneous complications of HCT
35 The microbiome and HCT
35 Cytokine release syndrome
36 Neurologic complications of CAR therapy
37 CAR therapy in ALL
37 Miscellaneous complications of CAR therapy
38 Symptom management and palliative care
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